With that many different hands, it is no longer necessary to vary your play on purpose to throw off your opponents. If your strategy is close to the chart suggested in this book, then you would be raising with about 25% of your hands in those situations.
In certain situations you won't have to adjust at all, such as when everyone has folded to you in late position. In games where you may be facing the same opponents routinely, it is useful to vary your play with starting hands to some degree. Of course you have equity in the pot as well as the other players, however, if your starting hand is poor, there is no reason to put in good money after bad money. You had to put them up regardless of the strength of your hand.
The chips you put up for the blinds are a sunk cost. It is important to think of the blinds that you had put up as part of the pot, not part of your stack. Many people think they need to defend their blinds all the time because they have already partially called and are getting to see a Flop at a 50% discount compared to other players.
